The main difference between a Bachelor of Innovation degree and a Bachelor of Science degree is in the electives. The Major part of the Bachelor of Science and Bachelor of Innovation degrees in any particular field have nearly identical coursework. In a Bachelor of Science the degree is an almost even split between General education (including structured electives) and Major Courses, while in a Bachelor of Innovation the innovation core covers most of the General education requirements, a few college level requirements, all while providing practical knowledge of the innovation process, entrepreneurship, how to work in teams, technical and proposal writing, business and intellectual property. The BI also structures many of the electives into one of four cross discipline core, each of which is a structure set of elective courses.
You can see a much more details on the program at http://innovation.uccs.edu/what-is-the-bi/